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RFA-HG-27-007

Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)

National Institutes of Health (HHS-NIH11)

Up to $2,000,000
Due Dec 14, 2026
At a glance
Complex

This grant is for organizations that want to study how changes in genes affect their function and the traits they influence. The goal is to use advanced methods to understand these changes and share the findings with a larger research community.

Who it's for: This grant is aimed at a wide range of entities, including government bodies, educational institutions, nonprofits, for-profit organizations, and individuals who are interested in genomic research.

More details

Likely Disqualifiers

  • Proposing a clinical trial
  • Not being part of a collaborative research effort
  • Inability to use high-throughput methods
  • Failure to develop data processing pipelines
  • Not coordinating with the IGVF Consortium

What You May Need

  • Detailed research proposal
  • Budget plan up to $2,000,000
  • Data sharing plan
  • Collaborative agreements
  • Proof of eligibility
  • Organizational capability statement
  • Letters of support
  • Curriculum vitae of key personnel
  • Documentation of high-throughput methods
  • Plan for reproducible data processing

Cautions

  • Clinical trials are not allowed
  • Must collaborate with the IGVF Consortium
  • High-throughput methods are required
  • Data must be made accessible to others

Generated from official source details for readability

Eligibility

Eligible Applicant Types

Private Higher Ed
Tribal Org
Nonprofit
County Gov
School Districts
Unrestricted
For-Profit
Public Higher Ed
Tribal Gov
Individuals
State Gov
Special District
City/Township
501(c)(3)

Additional Criteria

Eligible applicants include special district governments, independent school districts, state governments, private institutions of higher education, city or township governments, nonprofits without 501(c)(3) status, for-profit organizations, county governments, individuals, unrestricted applicants, other Native American tribal organizations, public and state institutions of higher education, nonprofits with 501(c)(3) status, and federally recognized Indian tribal governments.

Overview

This grant is aimed at a wide range of entities, including government bodies, educational institutions, nonprofits, for-profit organizations, and individuals who are interested in genomic research.

Likely Disqualifiers

  • Proposing a clinical trial
  • Not being part of a collaborative research effort
  • Inability to use high-throughput methods
  • Failure to develop data processing pipelines
  • Not coordinating with the IGVF Consortium

Use of Funds

Funds can be used to conduct genomic research, develop data processing tools, and collaborate with other research centers to share findings and resources.

Total Program Funding

$15,000,000

Expected Awards

5

Cost Sharing

Not Required

Important Dates

Posted
Oct 9, 2026
Deadline
Dec 14, 2026(65 days)
Archive Date
Feb 14, 2027

Application Checklist

0/9 complete
  • Register with NIH eRA Commons
  • Prepare a comprehensive research proposal
  • Develop a detailed budget plan
  • Create a data sharing and management plan
  • Gather letters of support and collaboration
  • Ensure all team members' CVs are updated
  • Outline high-throughput methods to be used
  • Plan for data processing and reproducibility
  • Submit application by December 14, 2026

Award Range

N/A - $2,000,000

Deadline

Dec 14, 2026

Total Program Funding

$15,000,000

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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