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RFA-DE-27-002

Accelerating Product Excellence in Innovation and for Clinical Adoption (APEx) (U24 Clinical Trial Not Allowed)

National Institutes of Health (HHS-NIH11)

Up to $4,000,000
Due Jul 10, 2026(13d left)
At a glance
Complex

The APEx grant from the National Institutes of Health is designed to support research in tissue engineering and regenerative medicine. It aims to help advance products and strategies that can detect or treat tissue damage from various causes. The grant will fund Resource Centers and Interdisciplinary Translational Projects that focus on therapeutics, sensors, and diagnostics, with the goal of getting these products ready for clinical trials.

Who it's for: This grant is for a wide range of entities including public and private institutions of higher education, state and local governments, federally recognized tribal governments, independent school districts, for-profit organizations, and nonprofits. It is especially suitable for those with expertise in tissue engineering and regenerative medicine.

More details

Likely Disqualifiers

  • Proposing a clinical trial
  • Lack of expertise in tissue engineering or regenerative medicine
  • Inadequate preclinical study plans
  • Failure to demonstrate regulatory and commercialization potential
  • Incomplete application

What You May Need

  • Detailed research proposal
  • Preclinical study plans
  • Regulatory and commercialization strategy
  • Budget justification
  • Institutional support letters
  • Proof of expertise in relevant fields
  • Project timeline
  • CVs of key personnel
  • Partnership agreements if applicable
  • Compliance with NIH guidelines

Cautions

  • Clinical trials are not allowed under this grant
  • Must focus on preclinical studies
  • Strong emphasis on regulatory and commercialization readiness
  • High competition due to broad eligibility

Generated from official source details for readability

Eligibility

Eligible Applicant Types

For-Profit
Tribal Org
Individuals
School Districts
City/Township
Public Higher Ed
Unrestricted
Nonprofit
State Gov
Special District
Tribal Gov
County Gov
Private Higher Ed
501(c)(3)

Additional Criteria

Eligible applicants include public and state institutions of higher education, federally recognized Indian tribal governments, individuals, state governments, independent school districts, county governments, special district governments, for-profit organizations, private institutions of higher education, nonprofits without 501(c)(3) status, city or township governments, nonprofits with 501(c)(3) status, and other Native American tribal organizations. This broad eligibility means many types of organizations can apply, but they must have a focus on tissue engineering and regenerative medicine.

Overview

This grant is for a wide range of entities including public and private institutions of higher education, state and local governments, federally recognized tribal governments, independent school districts, for-profit organizations, and nonprofits. It is especially suitable for those with expertise in tissue engineering and regenerative medicine.

Likely Disqualifiers

  • Proposing a clinical trial
  • Lack of expertise in tissue engineering or regenerative medicine
  • Inadequate preclinical study plans
  • Failure to demonstrate regulatory and commercialization potential
  • Incomplete application

Use of Funds

Funds can be used to support technical assistance, research capacity, administrative infrastructure, and regulatory and commercialization activities. This includes validation, manufacturing, and preclinical testing of products for tissue engineering and regenerative medicine.

Total Program Funding

$6,000,000

Cost Sharing

Not Required

Important Dates

Posted
May 4, 2026
Deadline
Jul 10, 2026(13 days)
Archive Date
Sep 8, 2026

Application Checklist

0/8 complete
  • Register with NIH eRA Commons
  • Prepare a comprehensive research proposal
  • Develop a detailed budget and justification
  • Gather letters of support from institutions
  • Ensure all key personnel have updated CVs
  • Outline a clear regulatory and commercialization plan
  • Compile preclinical study plans
  • Submit application by the deadline

Award Range

N/A - $4,000,000

Deadline

Jul 10, 2026

Total Program Funding

$6,000,000

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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