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RFA-RM-27-014

Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)

National Institutes of Health (HHS-NIH11)

Up to $2,000,000
Due Oct 2, 2026
At a glance
Complex

This grant is for creating a Validation Center to evaluate AI-based clinical decision support tools that integrate imaging with other health data. The goal is to ensure these tools are reliable and can be used in personalized medicine. The center will focus on testing and validating these tools to make sure they work well in real-world settings.

Who it's for: This grant is for organizations and entities that can establish a center dedicated to validating AI-based health tools. This includes state and local governments, educational institutions, tribal organizations, for-profit and nonprofit organizations, and individuals.

More details

Likely Disqualifiers

  • Proposing clinical trials
  • Lack of expertise in AI and health data integration
  • Inability to establish a dedicated validation center
  • Non-compliance with NIH guidelines
  • Incomplete application

What You May Need

  • Detailed project proposal
  • Budget plan
  • Organizational capability statement
  • Proof of eligibility
  • Partnership agreements (if applicable)
  • Data management plan
  • Letters of support
  • CVs of key personnel
  • Past performance documentation
  • Compliance with NIH policies

Cautions

  • Clinical trials are not allowed
  • Must focus on validation, not development
  • Ensure interoperability and uncertainty quantification
  • Strict adherence to NIH guidelines required

Generated from official source details for readability

Eligibility

Eligible Applicant Types

501(c)(3)
Special District
Public Higher Ed
State Gov
School Districts
City/Township
Tribal Org
Individuals
For-Profit
Unrestricted
Nonprofit
Tribal Gov
Private Higher Ed
County Gov

Additional Criteria

Eligible applicants include state governments, independent school districts, private institutions of higher education, other Native American tribal organizations, public and state institutions of higher education, individuals, special district governments, for-profit organizations, nonprofits without 501(c)(3) status, unrestricted entities, federally recognized Indian tribal governments, city or township governments, nonprofits with 501(c)(3) status, and county governments.

Overview

This grant is for organizations and entities that can establish a center dedicated to validating AI-based health tools. This includes state and local governments, educational institutions, tribal organizations, for-profit and nonprofit organizations, and individuals.

Likely Disqualifiers

  • Proposing clinical trials
  • Lack of expertise in AI and health data integration
  • Inability to establish a dedicated validation center
  • Non-compliance with NIH guidelines
  • Incomplete application

Use of Funds

Funds can be used to establish and operate a Validation Center for AI-based health tools, focusing on testing, validation, and integration into clinical workflows.

Total Program Funding

$2,700,000

Expected Awards

1

Cost Sharing

Not Required

Important Dates

Posted
Jun 30, 2026
Deadline
Oct 2, 2026(93 days)
Archive Date
Dec 1, 2026

Application Checklist

0/8 complete
  • Register with NIH eRA Commons
  • Prepare a detailed project narrative
  • Develop a comprehensive budget
  • Gather letters of support
  • Submit proof of eligibility
  • Ensure compliance with NIH policies
  • Complete all required forms
  • Submit application by deadline

Award Range

N/A - $2,000,000

Deadline

Oct 2, 2026

Total Program Funding

$2,700,000

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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