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RFA-HG-27-013

GREGoRi Innovation Projects (U01 Clinical Trial Optional)

National Institutes of Health (HHS-NIH11)

$3 - $500,000
Due Oct 30, 2026
At a glance
Moderate Complexity

The GREGoRi Innovation Projects grant aims to support groundbreaking research that improves how we diagnose rare genetic diseases. It encourages the development of new tools and methods, whether experimental or computational, to identify the genes or genetic variants causing these disorders.

Who it's for: This grant is for a wide range of applicants, including government entities, nonprofits, educational institutions, for-profit organizations, and individuals who are interested in advancing the diagnosis of rare genetic diseases through innovative research.

More details

Likely Disqualifiers

  • Applications lacking innovation
  • Projects not focused on rare genetic diseases
  • Incomplete applications
  • Requests exceeding $500,000
  • Non-compliance with NIH guidelines

What You May Need

  • Detailed project proposal
  • Budget plan
  • Proof of eligibility (e.g., 501(c)(3) status for nonprofits)
  • Research team qualifications
  • Project timeline
  • NIH biosketches for key personnel
  • Letters of support or collaboration
  • Institutional approval or endorsement
  • Data management plan
  • Human subjects protection plan (if applicable)

Cautions

  • Ensure the project aligns with the focus on rare genetic diseases.
  • Carefully adhere to NIH application guidelines.
  • Be aware of the funding cap of $500,000.
  • Consider the competitive nature of the grant.

Generated from official source details for readability

Eligibility

Eligible Applicant Types

Unrestricted
State Gov
Tribal Org
School Districts
Tribal Gov
Public Higher Ed
Individuals
For-Profit
County Gov
Nonprofit
City/Township
Private Higher Ed
501(c)(3)
Special District

Additional Criteria

Eligible applicants include special district governments, nonprofits with or without 501(c)(3) status, individuals, independent school districts, federally recognized Indian tribal governments, county governments, city or township governments, other Native American tribal organizations, state governments, public and state institutions of higher education, for-profit organizations, and private institutions of higher education.

Overview

This grant is for a wide range of applicants, including government entities, nonprofits, educational institutions, for-profit organizations, and individuals who are interested in advancing the diagnosis of rare genetic diseases through innovative research.

Likely Disqualifiers

  • Applications lacking innovation
  • Projects not focused on rare genetic diseases
  • Incomplete applications
  • Requests exceeding $500,000
  • Non-compliance with NIH guidelines

Use of Funds

Funds can be used to support the development and testing of new tools, technologies, and methods for diagnosing rare genetic diseases. This includes both experimental and computational approaches.

Total Program Funding

$7,500,000

Expected Awards

10

Cost Sharing

Not Required

Important Dates

Posted
Jun 18, 2026
Deadline
Oct 30, 2026(133 days)
Archive Date
Dec 9, 2026
Est. Award Date (AI estimate)
Winter 2027

Application Checklist

0/8 complete
  • Register with NIH eRA Commons
  • Prepare a detailed project proposal
  • Develop a comprehensive budget plan
  • Gather necessary institutional approvals
  • Complete NIH biosketches for all key personnel
  • Draft a data management plan
  • Prepare human subjects protection plan if needed
  • Submit application by the deadline

Award Range

$3 - $500,000

Deadline

Oct 30, 2026

Total Program Funding

$7,500,000

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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