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RFA-DC-27-004

BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)

National Institutes of Health (HHS-NIH11)

Up to $700,000
Due Feb 11, 2027
At a glance
Complex

This grant is for research projects that explore how brain activity relates to thoughts, emotions, and behaviors using invasive brain technologies. It aims to support early-stage research that could lead to more extensive studies in the future. The focus is on innovative human neuroscience research that leverages direct brain access during surgeries.

Who it's for: This grant is for researchers and institutions interested in studying brain activity using invasive technologies. Eligible applicants include universities, nonprofits, governments, tribal organizations, for-profit entities, and individuals.

More details

Likely Disqualifiers

  • Proposing a clinical trial
  • Lack of a multidisciplinary team
  • Not focusing on exploratory or early-stage research
  • Failure to address neuroethical considerations
  • Not participating in the NIH-coordinated consortium

What You May Need

  • Detailed research proposal
  • Budget plan
  • Proof of eligibility
  • Institutional support letters
  • Ethical compliance documentation
  • Data sharing plan
  • Consortium participation agreement
  • Project timeline
  • CVs of key personnel
  • Description of invasive technologies to be used

Cautions

  • No clinical trials allowed
  • Must participate in a consortium
  • Requires addressing neuroethical issues
  • Focus on exploratory research only
  • High level of scientific rigor expected

Generated from official source details for readability

Eligibility

Eligible Applicant Types

School Districts
Private Higher Ed
Individuals
Special District
Public Higher Ed
Tribal Org
City/Township
For-Profit
Unrestricted
County Gov
501(c)(3)
Nonprofit
State Gov
Tribal Gov

Additional Criteria

Eligible entities include private and public institutions of higher education, nonprofits with or without 501(c)(3) status, city or township governments, state governments, independent school districts, federally recognized Indian tribal governments, other Native American tribal organizations, unrestricted applicants, individuals, for-profit organizations, county governments, special district governments, and public and state institutions of higher education.

Overview

This grant is for researchers and institutions interested in studying brain activity using invasive technologies. Eligible applicants include universities, nonprofits, governments, tribal organizations, for-profit entities, and individuals.

Likely Disqualifiers

  • Proposing a clinical trial
  • Lack of a multidisciplinary team
  • Not focusing on exploratory or early-stage research
  • Failure to address neuroethical considerations
  • Not participating in the NIH-coordinated consortium

Use of Funds

Funds can be used for exploratory research and planning activities related to invasive brain recording and stimulation technologies. This includes feasibility studies, early-stage development, and data collection for further research.

Total Program Funding

$6,000,000

Expected Awards

5

Cost Sharing

Not Required

Important Dates

Posted
May 4, 2026
Deadline
Feb 11, 2027(229 days)
Archive Date
Apr 12, 2027
Est. Award Date (AI estimate)
Spring 2027

Application Checklist

0/10 complete
  • Ensure eligibility as per applicant types
  • Develop a multidisciplinary research team
  • Draft a detailed exploratory research proposal
  • Prepare a comprehensive budget plan
  • Gather institutional support letters
  • Address neuroethical considerations
  • Plan for data sharing and consortium participation
  • Submit CVs of all key personnel
  • Outline the use of invasive technologies
  • Submit application by the deadline

Award Range

N/A - $700,000

Deadline

Feb 11, 2027

Total Program Funding

$6,000,000

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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