The HeartShare 2.0 grant aims to fund a Clinical Trial Center (CTC) and up to seven Clinical Centers (CCs) to focus on heart failure research. The CTC will manage clinical trials, while the CCs will recruit patients and conduct research. This grant supports efforts to better understand heart failure with preserved ejection fraction (HFpEF) and improve treatment options.
Who it's for: This grant is for organizations and individuals interested in conducting heart failure research, specifically focusing on heart failure with preserved ejection fraction (HFpEF). Eligible applicants include a wide range of entities such as state and local governments, higher education institutions, nonprofits, for-profit organizations, tribal governments, and individuals.
More details
Likely Disqualifiers
- Submitting applications for both CTC and CC with the same Principal Investigator (PI)
- Failure to include CTC or CC in the project title
- Not meeting the application deadline
- Lack of experience in clinical trial coordination or patient recruitment
- Inadequate resources to conduct deep phenotyping protocols
What You May Need
- Detailed project proposal
- Separate Principal Investigators for CTC and CC applications
- Plan for patient recruitment and retention
- Experience with clinical trials and heart failure research
- Budget proposal
- Organizational capacity documentation
- Letters of support or collaboration
- Proof of eligibility (e.g., nonprofit status, government affiliation)
- Timeline for project milestones
- Plan for obtaining tissue biopsies
Cautions
- Ensure separate PIs for CTC and CC applications
- Include CTC or CC in the project title
- Adhere to the application deadline
- Prepare for extensive project management and scientific conduct responsibilities
Generated from official source details for readability
Eligibility
Eligible Applicant Types
Additional Criteria
Eligible applicants include state governments, county governments, private institutions of higher education, nonprofits with or without 501(c)(3) status, special district governments, for-profit organizations, federally recognized Indian tribal governments, city or township governments, public and state institutions of higher education, independent school districts, individuals, and other Native American tribal organizations. The eligibility is broad, allowing a wide range of entities to apply.
Overview
This grant is for organizations and individuals interested in conducting heart failure research, specifically focusing on heart failure with preserved ejection fraction (HFpEF). Eligible applicants include a wide range of entities such as state and local governments, higher education institutions, nonprofits, for-profit organizations, tribal governments, and individuals.
Likely Disqualifiers
- Submitting applications for both CTC and CC with the same Principal Investigator (PI)
- Failure to include CTC or CC in the project title
- Not meeting the application deadline
- Lack of experience in clinical trial coordination or patient recruitment
- Inadequate resources to conduct deep phenotyping protocols
Use of Funds
Funds can be used to coordinate and conduct clinical trials, recruit and retain patients, perform deep phenotyping, and support the scientific conduct of trials related to heart failure with preserved ejection fraction (HFpEF).
Total Program Funding
$3,465,000
Expected Awards
8
Cost Sharing
Not Required
Important Dates
- Posted
- May 19, 2026
- Deadline
- Jul 9, 2026(26 days)
- Archive Date
- Sep 7, 2026
- Est. Award Date (AI estimate)
- Fall 2026
Application Checklist
- Develop a detailed project proposal specific to CTC or CC
- Assign separate Principal Investigators for CTC and CC applications
- Include CTC or CC in the project title
- Prepare a budget proposal
- Gather letters of support or collaboration
- Document organizational capacity and experience
- Plan for patient recruitment and retention
- Outline a timeline for project milestones
- Submit proof of eligibility
- Ensure application is submitted by the deadline