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RFA-NS-28-012

Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)

National Institutes of Health (HHS-NIH11)

Up to $2,500,000
Due Oct 10, 2028
At a glance
Complex

This grant from the National Institutes of Health supports research into genomic and biologic therapies for Alzheimer's Disease-Related Dementias (ADRD). It covers everything from developing and optimizing therapies to early clinical trials. The goal is to advance treatments for conditions like Frontotemporal Dementia and Lewy Body Dementias.

Who it's for: This grant is for a wide range of applicants, including schools, universities, for-profit organizations, state and local governments, tribal governments, and nonprofits. It's ideal for those involved in genomic and biologic research related to dementia.

More details

Likely Disqualifiers

  • Lack of focus on ADRD
  • Inadequate research infrastructure
  • Non-compliance with NIH guidelines
  • Incomplete application
  • Lack of experience in clinical trials

What You May Need

  • Detailed research proposal
  • Budget plan
  • Proof of eligibility
  • Institutional support letter
  • Research team bios
  • Clinical trial plans (if applicable)
  • Regulatory compliance documentation
  • Previous research outcomes
  • Timeline for project milestones
  • Data management plan

Cautions

  • Ensure alignment with NIH regulatory expectations
  • Focus on ADRD-specific therapies
  • Strict adherence to clinical trial protocols
  • Comprehensive safety and toxicology studies required

Generated from official source details for readability

Eligibility

Eligible Applicant Types

Individuals
Tribal Org
Nonprofit
State Gov
Tribal Gov
Private Higher Ed
City/Township
Unrestricted
Special District
School Districts
County Gov
501(c)(3)
For-Profit
Public Higher Ed

Additional Criteria

Eligible applicants include independent school districts, private and public institutions of higher education, for-profit organizations, state governments, individuals, city or township governments, federally recognized Indian tribal governments, county governments, nonprofits with or without 501(c)(3) status, other Native American tribal organizations, and special district governments. This broad eligibility allows a diverse range of entities to apply, provided they focus on genomic and biologic therapies for ADRD.

Overview

This grant is for a wide range of applicants, including schools, universities, for-profit organizations, state and local governments, tribal governments, and nonprofits. It's ideal for those involved in genomic and biologic research related to dementia.

Likely Disqualifiers

  • Lack of focus on ADRD
  • Inadequate research infrastructure
  • Non-compliance with NIH guidelines
  • Incomplete application
  • Lack of experience in clinical trials

Use of Funds

Funds can be used for developing and optimizing therapies, conducting safety and efficacy studies, and preparing for clinical trials. This includes costs related to research, personnel, and necessary equipment.

Total Program Funding

$6,000,000

Expected Awards

3

Cost Sharing

Not Required

Important Dates

Posted
Nov 3, 2026
Deadline
Oct 10, 2028(706 days)
Archive Date
Dec 9, 2028

Application Checklist

0/10 complete
  • Register with NIH eRA Commons
  • Prepare a detailed research proposal focused on ADRD
  • Develop a comprehensive budget plan
  • Gather institutional support and commitment letters
  • Compile bios and qualifications of research team
  • Outline clinical trial plans, if applicable
  • Ensure compliance with NIH guidelines
  • Submit proof of eligibility
  • Create a timeline for project milestones
  • Draft a data management plan

Award Range

N/A - $2,500,000

Deadline

Oct 10, 2028

Total Program Funding

$6,000,000

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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