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PAR-25-154
Simpler.Grants.gov

HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)

National Institutes of Health (HHS-NIH11)

Up to $100,000
Due Jul 16, 2026
At a glance
Complex

This grant is looking for projects that explore new ways to target pain through proteins that haven't been studied much. It's part of a larger effort to find new treatments for pain and opioid addiction. The grant provides up to $100,000 to help researchers gather initial data or develop tools related to these proteins.

Who it's for: This grant is for researchers and organizations interested in studying proteins related to pain management. Eligible applicants include various government entities, nonprofits, small businesses, and educational institutions.

More details

Likely Disqualifiers

  • Proposing a clinical trial
  • Not focusing on understudied proteins listed in the NOFO
  • Requesting more than $100,000
  • Not aligning with the HEAL initiative goals
  • Incomplete application

What You May Need

  • Detailed project proposal
  • Preliminary data or research plan
  • Budget justification
  • Proof of eligibility (e.g., 501(c)(3) status for nonprofits)
  • Institutional support letters
  • Research team bios
  • Timeline for project completion
  • Description of how the project aligns with HEAL initiative goals
  • Registration with NIH's electronic submission system

Cautions

  • Clinical trials are not allowed
  • Must focus on proteins listed in the NOFO
  • Strict adherence to HEAL initiative goals
  • Ensure all application components are complete and submitted on time

Generated from official source details for readability

Eligibility

Eligible Applicant Types

Tribal Org
Special District
City/Township
Tribal Gov
Small Business
501(c)(3)
School Districts
For-Profit
Public Higher Ed
State Gov
Public Higher Ed
Nonprofit
County Gov
Private Higher Ed
Other

Additional Criteria

Eligible applicants include: Other Native American tribal organizations, special district governments, city or township governments, federally recognized Indian tribal governments, small businesses, nonprofits with 501(c)(3) status, independent school districts, for-profit organizations, public and state institutions of higher education, state governments, nonprofits without 501(c)(3) status, county governments, and private institutions of higher education.

Overview

This grant is for researchers and organizations interested in studying proteins related to pain management. Eligible applicants include various government entities, nonprofits, small businesses, and educational institutions.

Likely Disqualifiers

  • Proposing a clinical trial
  • Not focusing on understudied proteins listed in the NOFO
  • Requesting more than $100,000
  • Not aligning with the HEAL initiative goals
  • Incomplete application

Use of Funds

Funds can be used to generate preliminary data or develop tools related to understudied proteins in pain research. This includes basic biochemical or biological work to better understand these proteins.

Cost Sharing

Not Required

Important Dates

Posted
Dec 11, 2024
Deadline
Jul 16, 2026(33 days)
Archive Date
Aug 21, 2026

Application Checklist

0/6 complete
  • Review NOFO for eligible proteins
  • Develop a research proposal focusing on understudied proteins
  • Prepare a detailed budget and justification
  • Gather institutional support and letters
  • Register and submit through NIH's electronic system
  • Ensure alignment with HEAL initiative goals

Award Range

N/A - $100,000

Deadline

Jul 16, 2026

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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