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RFA-HG-27-009
Simpler.Grants.gov

Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)

National Institutes of Health (HHS-NIH11)

Up to $1,500,000
Due Dec 14, 2026
At a glance
Complex

This grant is for research centers to study how genetic or environmental factors interact with genomic variants. The goal is to understand these interactions better and improve predictions for testing genetic variants. Centers will share their findings and methods to help others in the field.

Who it's for: This grant is for organizations like nonprofits, state and local governments, schools, tribal governments, small businesses, and higher education institutions that are interested in genomic research.

More details

Likely Disqualifiers

  • Proposing clinical trials
  • Not sharing data through the IGVF portal
  • Lack of collaboration with IGVF Consortium
  • Inadequate research framework
  • Failure to coordinate with other consortium components

What You May Need

  • Research framework proposal
  • Plan for data sharing via IGVF portal
  • Collaboration plan with IGVF Consortium
  • Budget proposal
  • Organizational eligibility documentation
  • Detailed project timeline
  • Method for predicting important combinations
  • Assay, variant, and cell type coordination plan
  • Shared analysis strategy

Cautions

  • Clinical trials are not allowed
  • Must collaborate with IGVF Consortium
  • Data and analysis must be shared publicly
  • Research must focus on interactions beyond additive effects

Generated from official source details for readability

Eligibility

Eligible Applicant Types

Nonprofit
State Gov
School Districts
County Gov
501(c)(3)
Tribal Gov
Small Business
Private Higher Ed
For-Profit
Public Higher Ed
City/Township
Special District
Tribal Org
Public Higher Ed
Other

Additional Criteria

Eligible applicants include nonprofits (with or without 501(c)(3) status), state governments, independent school districts, county governments, federally recognized Indian tribal governments, small businesses, private and public institutions of higher education, for-profit organizations, city or township governments, special district governments, and other Native American tribal organizations.

Overview

This grant is for organizations like nonprofits, state and local governments, schools, tribal governments, small businesses, and higher education institutions that are interested in genomic research.

Likely Disqualifiers

  • Proposing clinical trials
  • Not sharing data through the IGVF portal
  • Lack of collaboration with IGVF Consortium
  • Inadequate research framework
  • Failure to coordinate with other consortium components

Use of Funds

Funds can be used for research into genetic and environmental interactions with genomic variants, data sharing, and collaboration within the IGVF Consortium.

Total Program Funding

$10,000,000

Expected Awards

5

Cost Sharing

Not Required

Important Dates

Posted
Oct 9, 2026
Deadline
Dec 14, 2026(65 days)
Archive Date
Feb 14, 2027
Last Updated
Oct 9, 2026
Est. Award Date (AI estimate)
Spring 2027

Application Checklist

0/9 complete
  • Verify organizational eligibility
  • Develop a detailed research framework
  • Prepare a data sharing plan for the IGVF portal
  • Create a collaboration strategy with IGVF Consortium
  • Draft a comprehensive budget
  • Compile necessary organizational documents
  • Design a method for predicting important variant combinations
  • Coordinate assay, variant, and cell type plans
  • Establish a shared analysis strategy

Award Range

N/A - $1,500,000

Deadline

Dec 14, 2026

Total Program Funding

$10,000,000

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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