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PAR-25-446
Simpler.Grants.gov

Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

National Institutes of Health (HHS-NIH11)

Up to $3,000,000
Due Aug 21, 2028
At a glance
Moderate Complexity

This grant is for research projects aimed at developing new ways to prevent and treat substance use disorders and overdoses. It's open to a wide range of organizations and focuses on both early-stage and clinical research that can quickly lead to new treatments or devices being approved or used in healthcare.

Who it's for: This grant is for organizations like universities, nonprofits, small businesses, and government entities that are involved in research and development of treatments for substance use disorders and overdoses.

More details

Likely Disqualifiers

  • Individuals applying independently
  • Organizations without a research focus
  • Entities not involved in substance use disorder interventions
  • Applications not aligned with the grant's focus on SUDs and overdose
  • Incomplete applications

What You May Need

  • Detailed research proposal
  • Proof of organizational eligibility
  • Budget plan up to $3,000,000
  • Project timeline
  • Regulatory compliance plans
  • Letters of support or collaboration
  • Previous research outcomes (if applicable)
  • Organizational financial documents
  • Registration with NIH's electronic systems

Cautions

  • Ensure research aligns with the grant's focus on SUDs and overdose
  • Strict adherence to NIH guidelines and regulations
  • Potentially competitive due to broad eligibility
  • Complex application process requiring detailed documentation

Generated from official source details for readability

Eligibility

Eligible Applicant Types

City/Township
Public Higher Ed
501(c)(3)
State Gov
Tribal Gov
County Gov
For-Profit
Public Higher Ed
Special District
School Districts
Nonprofit
Tribal Org
Other
Small Business
Private Higher Ed

Additional Criteria

Eligible applicants include city or township governments, public and state institutions of higher education, nonprofits with or without 501(c)(3) status, state governments, federally recognized Indian tribal governments, county governments, for-profit organizations, special district governments, independent school districts, other Native American tribal organizations, small businesses, and private institutions of higher education.

Overview

This grant is for organizations like universities, nonprofits, small businesses, and government entities that are involved in research and development of treatments for substance use disorders and overdoses.

Likely Disqualifiers

  • Individuals applying independently
  • Organizations without a research focus
  • Entities not involved in substance use disorder interventions
  • Applications not aligned with the grant's focus on SUDs and overdose
  • Incomplete applications

Use of Funds

Funds can be used for research activities related to developing interventions for substance use disorders and overdose, including both preclinical and clinical studies. This may cover personnel, equipment, materials, and other research-related expenses.

Cost Sharing

Not Required

Important Dates

Posted
Sep 10, 2025
Deadline
Aug 21, 2028(800 days)
Archive Date
Sep 26, 2028
Last Updated
May 13, 2026

Application Checklist

0/9 complete
  • Register with NIH's electronic systems
  • Prepare a comprehensive research proposal
  • Gather organizational eligibility documents
  • Develop a detailed budget plan
  • Outline a project timeline
  • Ensure compliance with regulatory requirements
  • Obtain letters of support or collaboration
  • Compile previous research outcomes (if applicable)
  • Submit application before the deadline

Award Range

N/A - $3,000,000

Deadline

Aug 21, 2028

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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