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RFA-NS-25-022
Simpler.Grants.gov

BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)

National Institutes of Health (HHS-NIH11)

Due Sep 28, 2026
At a glance
Complex

This grant is for researchers who want to conduct small clinical trials to test new devices that record or stimulate the brain. These trials help gather important information needed to improve these devices, which could treat brain disorders or help us understand the brain better. The trials can be short-term and low-risk or involve more significant risk, needing special approval. The goal is to gather data that can't be obtained through other methods like lab or animal studies.

Who it's for: This grant is suitable for a wide range of applicants, including public and private universities, non-profit organizations, small businesses, state and local governments, tribal organizations, and for-profit entities. It's ideal for those involved in clinical research and development of brain-related devices.

More details

Likely Disqualifiers

  • Lack of IRB approval for NSR studies
  • No FDA IDE for SR studies
  • Insufficient existing safety and utility data
  • Proposals not involving clinical trials
  • Proposals not focused on brain-related devices

What You May Need

  • Institutional Review Board (IRB) approval
  • Investigational Device Exemption (IDE) from FDA
  • Detailed clinical trial plan
  • Partnership with device manufacturers
  • Existing safety and utility data
  • Memoranda of Understanding (MOU) with manufacturers
  • Budget proposal
  • Research team qualifications
  • Timeline for clinical trial
  • Non-clinical testing data

Cautions

  • Ensure all necessary approvals are obtained before applying
  • Device must have sufficient existing data for safety and utility
  • Trial must provide unique data not obtainable through other methods
  • Partnerships with manufacturers may be required

Generated from official source details for readability

Eligibility

Eligible Applicant Types

Public Higher Ed
Nonprofit
Tribal Org
501(c)(3)
Small Business
School Districts
State Gov
Public Higher Ed
Tribal Gov
County Gov
Private Higher Ed
For-Profit
City/Township
Special District
Other

Additional Criteria

This grant is suitable for a wide range of applicants, including public and private universities, non-profit organizations, small businesses, state and local governments, tribal organizations, and for-profit entities. It's ideal for those involved in clinical research and development of brain-related devices.

Overview

This grant is suitable for a wide range of applicants, including public and private universities, non-profit organizations, small businesses, state and local governments, tribal organizations, and for-profit entities. It's ideal for those involved in clinical research and development of brain-related devices.

Likely Disqualifiers

  • Lack of IRB approval for NSR studies
  • No FDA IDE for SR studies
  • Insufficient existing safety and utility data
  • Proposals not involving clinical trials
  • Proposals not focused on brain-related devices

Use of Funds

Funds can be used to conduct small clinical trials that test the function and design of new brain-related devices. This includes covering costs related to trial setup, data collection, and analysis, as well as obtaining necessary approvals and partnerships.

Cost Sharing

Not Required

Important Dates

Posted
Nov 5, 2024
Deadline
Sep 28, 2026(107 days)
Archive Date
Nov 3, 2026
Last Updated
Nov 14, 2024
Est. Award Date (AI estimate)
Winter 2026

Application Checklist

0/10 complete
  • Confirm eligibility as an applicant type
  • Secure IRB approval for NSR studies
  • Obtain FDA IDE for SR studies
  • Develop a detailed clinical trial proposal
  • Gather existing safety and utility data
  • Establish partnerships with device manufacturers
  • Draft a budget and timeline for the trial
  • Prepare team qualifications and experience documentation
  • Submit Memoranda of Understanding (MOU) if applicable
  • Ensure trial addresses unique data collection needs

Award Range

Not specified

Deadline

Sep 28, 2026

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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