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PAR-25-211
Simpler.Grants.gov

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

National Institutes of Health (HHS-NIH11)

Due Jun 2, 2027
At a glance
Complex

This grant is designed to fund research that explores how different people respond to probiotics. The goal is to understand why probiotics work differently for different people and to develop strategies to improve their effectiveness. The funding is split into two phases: the first phase focuses on identifying patterns in people's biology that affect probiotic responses, and the second phase tests these patterns to improve probiotic effectiveness.

Who it's for: This grant is for a wide range of organizations, including universities, nonprofits, government bodies, and businesses, that are interested in conducting innovative research on probiotics. Ideal applicants are those with a strong background in health and education research, particularly in the field of probiotics and personalized medicine.

More details

Likely Disqualifiers

  • Failure to specify clear Transition Milestones for the R61 phase
  • Lack of innovative mechanistic research proposal
  • Inability to demonstrate expertise in probiotics or related fields
  • Non-compliance with NIH application requirements
  • Proposals that do not address the heterogeneity in probiotic responses

What You May Need

  • Detailed research proposal
  • Plan for identifying unique host biological patterns
  • Description of observational or secondary data analysis methods
  • Transition Milestones for R61 to R33 phase
  • Budget justification
  • Institutional support letters
  • Proof of eligibility (e.g., 501(c)(3) status for nonprofits)
  • Research team bios and qualifications
  • Human or animal study protocols, if applicable
  • NIH biosketches for key personnel

Cautions

  • Ensure all milestones for the R61 phase are clearly defined
  • Transition from R61 to R33 is not guaranteed and requires administrative review
  • Proposals must be highly innovative and mechanistic
  • The total project period cannot exceed 5 years

Generated from official source details for readability

Eligibility

Eligible Applicant Types

Public Higher Ed
Tribal Org
Special District
Public Higher Ed
County Gov
Other
501(c)(3)
For-Profit
City/Township
Tribal Gov
State Gov
Private Higher Ed
School Districts
Nonprofit
Small Business

Additional Criteria

This grant is for a wide range of organizations, including universities, nonprofits, government bodies, and businesses, that are interested in conducting innovative research on probiotics. Ideal applicants are those with a strong background in health and education research, particularly in the field of probiotics and personalized medicine.

Overview

This grant is for a wide range of organizations, including universities, nonprofits, government bodies, and businesses, that are interested in conducting innovative research on probiotics. Ideal applicants are those with a strong background in health and education research, particularly in the field of probiotics and personalized medicine.

Likely Disqualifiers

  • Failure to specify clear Transition Milestones for the R61 phase
  • Lack of innovative mechanistic research proposal
  • Inability to demonstrate expertise in probiotics or related fields
  • Non-compliance with NIH application requirements
  • Proposals that do not address the heterogeneity in probiotic responses

Use of Funds

Funds can be used to conduct research that identifies biological patterns affecting probiotic responses and to test these patterns in improving probiotic effectiveness. This includes funding for data analysis, research personnel, and potentially animal or human studies.

Cost Sharing

Not Required

Important Dates

Posted
Oct 31, 2024
Deadline
Jun 2, 2027(354 days)
Archive Date
Jul 8, 2027
Last Updated
Oct 31, 2024
Est. Award Date (AI estimate)
Fall 2027

Application Checklist

0/10 complete
  • Develop a detailed research proposal focusing on precision probiotic therapies
  • Identify and outline unique host biological patterns to study
  • Prepare a plan for observational or secondary data analysis
  • Define clear Transition Milestones for the R61 phase
  • Compile a budget and justification
  • Gather institutional support letters
  • Ensure all team members have updated NIH biosketches
  • Prepare protocols for human or animal studies, if applicable
  • Verify eligibility and gather necessary documentation
  • Submit application by the deadline: June 2, 2027

Award Range

Not specified

Deadline

Jun 2, 2027

Official Source

Always review the official grant listing for the most accurate and up-to-date information.

View Official Listing

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